GPAM Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9HCL2 |
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Other Accession | NP_065969.3 |
Clone Names | 90805037 |
Gene ID | 57678 |
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Other Names | Glycerol-3-phosphate acyltransferase 1, mitochondrial, GPAT-1, GPAM, GPAT1, KIAA1560 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | GPAM (HGNC:24865) |
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Synonyms | GPAT1, KIAA1560 |
Function | Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipids biosynthesis such as triglycerides, phosphatidic acids and lysophosphatidic acids. |
Cellular Location | Mitochondrion outer membrane {ECO:0000250|UniProtKB:P97564}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P97564} |
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Provided below are standard protocols that you may find useful for product applications.
Background
Glycerol-3-phosphate acyltransferase (GPAT; EC 2.3.1.15),which catalyzes the initial and committing step in glycerolipidbiosynthesis, is predicted to play a pivotal role in the regulationof cellular triacylglycerol and phospholipid levels. Two mammalianforms of GPAT have been identified on the basis of localization toeither the endoplasmic reticulum or mitochondria.[supplied byOMIM].
References
Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)Reiling, E., et al. Eur. J. Hum. Genet. 17(8):1056-1062(2009)Lu, Y., et al. J. Lipid Res. 49(12):2582-2589(2008)Chen, Y.Q., et al. J. Biol. Chem. 283(15):10048-10057(2008)Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
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