|Other Names||Glycerol-3-phosphate acyltransferase 1, mitochondrial, GPAT-1, GPAM, GPAT1, KIAA1560|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis.|
|Cellular Location||Mitochondrion outer membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Glycerol-3-phosphate acyltransferase (GPAT; EC 220.127.116.11),which catalyzes the initial and committing step in glycerolipidbiosynthesis, is predicted to play a pivotal role in the regulationof cellular triacylglycerol and phospholipid levels. Two mammalianforms of GPAT have been identified on the basis of localization toeither the endoplasmic reticulum or mitochondria.[supplied byOMIM].
Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)Reiling, E., et al. Eur. J. Hum. Genet. 17(8):1056-1062(2009)Lu, Y., et al. J. Lipid Res. 49(12):2582-2589(2008)Chen, Y.Q., et al. J. Biol. Chem. 283(15):10048-10057(2008)Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
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