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PP1R14C Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8TAE6 |
|---|---|
| Other Accession | NP_112211.1 |
| Clone Names | 90805089 |
| Gene ID | 81706 |
|---|---|
| Other Names | Protein phosphatase 1 regulatory subunit 14C, Kinase-enhanced PP1 inhibitor, PKC-potentiated PP1 inhibitory protein, Serologically defined breast cancer antigen NY-BR-81, PPP1R14C, KEPI |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PPP1R14C |
|---|---|
| Synonyms | KEPI |
| Function | Inhibitor of the PP1 regulatory subunit PPP1CA. |
| Cellular Location | Cytoplasm. Membrane; Peripheral membrane protein |
| Tissue Location | Detected in breast cancer. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The degree of protein phosphorylation is regulated by abalance of protein kinase and phosphatase activities. Proteinphosphatase-1 (PP1; see MIM 176875) is a signal-transducingphosphatase that influences neuronal activity, protein synthesis,metabolism, muscle contraction, and cell division. PPP1R14C is aninhibitor of PP1 (Liu et al., 2002 [PubMed 11812771]).[supplied byOMIM].
References
Daskalow, K., et al. Anticancer Res. 30(5):1573-1578(2010)Scholz, S.W., et al. Ann. Neurol. 65(5):610-614(2009)Burgner, D., et al. PLoS Genet. 5 (1), E1000319 (2009) :Mungall, A.J., et al. Nature 425(6960):805-811(2003)Liu, Q.R., et al. J. Biol. Chem. 277(15):13312-13320(2002)
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