|Other Names||Protein phosphatase 1 regulatory subunit 14C, Kinase-enhanced PP1 inhibitor, PKC-potentiated PP1 inhibitory protein, Serologically defined breast cancer antigen NY-BR-81, PPP1R14C, KEPI|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Inhibitor of the PP1 regulatory subunit PPP1CA.|
|Cellular Location||Cytoplasm. Membrane; Peripheral membrane protein|
|Tissue Location||Detected in breast cancer.|
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The degree of protein phosphorylation is regulated by abalance of protein kinase and phosphatase activities. Proteinphosphatase-1 (PP1; see MIM 176875) is a signal-transducingphosphatase that influences neuronal activity, protein synthesis,metabolism, muscle contraction, and cell division. PPP1R14C is aninhibitor of PP1 (Liu et al., 2002 [PubMed 11812771]).[supplied byOMIM].
Daskalow, K., et al. Anticancer Res. 30(5):1573-1578(2010)Scholz, S.W., et al. Ann. Neurol. 65(5):610-614(2009)Burgner, D., et al. PLoS Genet. 5 (1), E1000319 (2009) :Mungall, A.J., et al. Nature 425(6960):805-811(2003)Liu, Q.R., et al. J. Biol. Chem. 277(15):13312-13320(2002)
If you have any additional inquiries please email technical services at email@example.com.