|Other Accession||NP_808818.1, NP_055597.1|
|Other Names||Armadillo repeat-containing X-linked protein 2, ARM protein lost in epithelial cancers on chromosome X 2, Protein ALEX2, ARMCX2, ALEX2, KIAA0512|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Membrane; Single-pass membrane protein|
|Tissue Location||Expressed at high levels ovary, heart, testis, prostate, brain, spleen and colon. Expressed at very low levels in liver and thymus. Not expressed in peripheral blood leukocytes Not expressed in pancreas and ovarian carcinomas|
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This gene encodes a member of the ALEX family of proteinsand may play a role in tumor suppression. The encoded proteincontains a potential N-terminal transmembrane domain and a singleArmadillo (arm) repeat. Other proteins containing the arm repeatare involved in development, maintenance of tissue integrity, andtumorigenesis. This gene is closely localized with other familymembers, including ALEX1 and ALEX3, on the X chromosome. Twoalternative transcripts that encode the same protein but differ inthe 5' UTR have been described. Additional alternative transcriptsmay exist but their full length natures have not been determined. Apseudogene for this locus is located on chromosome 7. [provided byRefSeq].
Ross, M.T., et al. Nature 434(7031):325-337(2005)Goehler, H., et al. Mol. Cell 15(6):853-865(2004)Kurochkin, I.V., et al. Biochem. Biophys. Res. Commun. 280(1):340-347(2001)
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