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PEX1 Antibody (Center) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession O43933
Other Accession NP_000457.1
Clone Names 90909082
Peptide ID 90909082
Additional Information
Gene ID 5189
Other Names Peroxisome biogenesis factor 1, Peroxin-1, Peroxisome biogenesis disorder protein 1, PEX1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PEX1
Function Required for stability of PEX5 and protein import into the peroxisome matrix. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes.
Cellular Location Cytoplasm. Peroxisome membrane. Note=Associated with peroxisomal membranes
Research Areas
Citations (0)

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Background

This gene encodes a member of the AAA ATPase family, alarge group of ATPases associated with diverse cellular activities.This protein is cytoplasmic but is often anchored to a peroxisomalmembrane where it forms a heteromeric complex and plays a role inthe import of proteins into peroxisomes and peroxisome biogenesis.Mutations in this gene have been associated with complementationgroup 1 peroxisomal disorders such as neonataladrenoleukodystrophy, infantile Refsum disease, and Zellwegersyndrome.

References

Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :Yik, W.Y., et al. Hum. Mutat. 30 (3), E467-E480 (2009) :Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)Matsuoka, S., et al. Science 316(5828):1160-1166(2007)Tamura, S., et al. J. Biol. Chem. 281(38):27693-27704(2006)

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$ 80.00
Cat# BP10181c
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