|Other Accession||NP_001127697.1, NP_001127696.1, NP_004018.1, NP_001557.1|
|Other Names||Type I inositol 3, 4-bisphosphate 4-phosphatase, Inositol polyphosphate 4-phosphatase type I, INPP4A|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4- trisphosphate and inositol 3,4-bisphosphate.|
|Tissue Location||Isoform 1 is expressed in the platelets, MEG- 01 megakaryocytes and Jurkat T-cells. Isoform 2 is expressed in the brain.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes an Mg++ independent enzyme thathydrolyzes the 4-position phosphate from the inositol ring ofphosphatidylinositol 3,4-bisphosphate, inositol1,3,4-trisphosphate, and inositol 3,4-bisphosphate. Multipletranscript variants encoding distinct isoforms have been described.
Sasaki, J., et al. Nature 465(7297):497-501(2010)Rogers, A.J., et al. Am. J. Respir. Crit. Care Med. 179(12):1084-1090(2009)Kobayashi, S., et al. DNA Res. 15(4):253-265(2008)Sharma, M., et al. Am. J. Respir. Crit. Care Med. 177(7):712-719(2008)Hillier, L.W., et al. Nature 434(7034):724-731(2005)
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