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HOXD12 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession P35452
Other Accession NP_067016.3
Clone Names 91023114
Additional Information
Gene ID 3238
Other Names Homeobox protein Hox-D12, Homeobox protein Hox-4H, HOXD12, HOX4H
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HOXD12
Synonyms HOX4H
Function Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Cellular Location Nucleus.
Research Areas
Citations (0)
citation

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Background

This gene belongs to the homeobox family of genes. Thehomeobox genes encode a highly conserved family of transcriptionfactors that play an important role in morphogenesis in allmulticellular organisms. Mammals possess four similar homeobox geneclusters, HOXA, HOXB, HOXC and HOXD, located on differentchromosomes, consisting of 9 to 11 genes arranged in tandem. Thisgene is one of several homeobox HOXD genes located in a cluster onchromosome 2. Deletions that remove the entire HOXD gene cluster orthe 5' end of this cluster have been associated with severe limband genital abnormalities. The exact role of this gene has not beendetermined.

References

Sugie, Y., et al. Brain Dev. 32(5):356-361(2010)Woo, C.J., et al. Cell 140(1):99-110(2010)Ester, A.R., et al. Am. J. Med. Genet. A 149A (12), 2745-2752 (2009) :Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)Zhao, X., et al. Am. J. Hum. Genet. 80(2):361-371(2007)

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$ 277.78
Cat# BP10198b
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