|Other Names||Solute carrier family 2, facilitated glucose transporter member 12, Glucose transporter type 12, GLUT-12, SLC2A12, GLUT12, GLUT8|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Facilitative glucose transporter.|
|Cellular Location||Endomembrane system; Multi- pass membrane protein. Cytoplasm, perinuclear region. Note=Localizes primarily perinuclear region in the absence of insulin|
|Tissue Location||Predominantly expressed in skeletal muscle, heart and prostate, with lower levels in brain, placenta and kidney.|
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Provided below are standard protocols that you may find useful for product applications.
SLC2A12 belongs to a family of transporters that catalyzethe uptake of sugars through facilitated diffusion (Rogers et al.,2002). This family of transporters show conservation of 12transmembrane helices as well as functionally significant aminoacid residues (Joost and Thorens, 2001 [PubMed 11780753]).[suppliedby OMIM].
Stuart, C.A., et al. J. Clin. Endocrinol. Metab. 94(9):3535-3542(2009)Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008)Stuart, C.A., et al. Am. J. Physiol. Endocrinol. Metab. 291 (5), E1067-E1073 (2006) :Linden, K.C., et al. Am. J. Physiol. Renal Physiol. 290 (1), F205-F213 (2006) :Rogers, S., et al. Biochem. Biophys. Res. Commun. 308(3):422-426(2003)
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