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SLC2A12 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8TD20
Other Accession NP_660159.1
Clone Names 91102072
Additional Information
Gene ID 154091
Other Names Solute carrier family 2, facilitated glucose transporter member 12, Glucose transporter type 12, GLUT-12, SLC2A12, GLUT12, GLUT8
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC2A12 (HGNC:18067)
Function Insulin-independent facilitative glucose transporter.
Cellular Location Cell membrane {ECO:0000250|UniProtKB:Q8BFW9}; Multi-pass membrane protein. Endomembrane system {ECO:0000250|UniProtKB:Q5J316}; Multi-pass membrane protein. Cytoplasm, perinuclear region. Note=Localizes primarily perinuclear region in the absence of insulin.
Tissue Location Predominantly expressed in skeletal muscle, heart and prostate, with lower levels in brain, placenta and kidney
Research Areas
Citations (0)
citation

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Background

SLC2A12 belongs to a family of transporters that catalyzethe uptake of sugars through facilitated diffusion (Rogers et al.,2002). This family of transporters show conservation of 12transmembrane helices as well as functionally significant aminoacid residues (Joost and Thorens, 2001 [PubMed 11780753]).[suppliedby OMIM].

References

Stuart, C.A., et al. J. Clin. Endocrinol. Metab. 94(9):3535-3542(2009)Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008)Stuart, C.A., et al. Am. J. Physiol. Endocrinol. Metab. 291 (5), E1067-E1073 (2006) :Linden, K.C., et al. Am. J. Physiol. Renal Physiol. 290 (1), F205-F213 (2006) :Rogers, S., et al. Biochem. Biophys. Res. Commun. 308(3):422-426(2003)

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$ 277.78
Cat# BP10200b
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