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FPRL1 Antibody (Center) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession P25090
Other Accession NP_001005738.1, NP_001453.1
Clone Names 90625034
Peptide ID 90625034
Additional Information
Gene ID 2358
Other Names N-formyl peptide receptor 2, FMLP-related receptor I, FMLP-R-I, Formyl peptide receptor-like 1, HM63, Lipoxin A4 receptor, LXA4 receptor, RFP, FPR2, FPRH1, FPRL1, LXA4R
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name FPR2
Synonyms FPRH1, FPRL1, LXA4R
Function Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Expressed abundantly in the lung and neutrophils. Also found in the spleen and testis
Research Areas
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References

Yang, E.M., et al. Ann. Allergy Asthma Immunol. 105(1):96-97(2010)Kretschmer, D., et al. Cell Host Microbe 7(6):463-473(2010)Lee, H.Y., et al. Exp. Mol. Med. 42(4):302-309(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)Kim, S.D., et al. J. Immunol. 183(9):5511-5517(2009)

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$ 80.00
Cat# BP10206c
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