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GCNT2 Antibody (C-term) Blocking peptideSynthetic peptide
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| BP10215b | 0.1 mg 400 ul | In Stock | $ 45.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
GCNT2 Antibody (C-term) Blocking peptide - Product info | |
| Primary Accession | Q06430 |
| Other Accession | NP_001482.1 |
| Clone Names | 91013003 |
| Calculated MW | 45855 Da |
GCNT2 Antibody (C-term) Blocking peptide - Additional info | |
| Gene ID 2651 | |
| Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
GCNT2 Antibody (C-term) Blocking peptide - Protein Information | |
| Name GCNT2 | |
| Synonyms GCNT5, II, NACGT1 | |
| Function Branching enzyme that converts linear into branched poly-N-acetyllactosaminoglycans. Introduces the blood group I antigen during embryonic development. It is closely associated with the development and maturation of erythroid cells. The expression of the blood group I antigen in erythrocytes is determined by isoform C | |
| Cellular Location Golgi apparatus membrane; Single-pass type II membrane protein | |
| Tissue Location In the adult, highly expressed in prostate and to a lesser extent in small intestine and colon. Barely detected in heart, brain, kidney and pancreas. No expression in placenta, lung, liver, skeletal muscle, spleen, thymus, testis, ovary and peripheral blood leukocytes. In fetus, highly expressed in brain and to a lesser extent in lung and kidney. Barely detected in liver | |
GCNT2 Antibody (C-term) Blocking peptide - Related products
GCNT2 Antibody (C-term) Blocking peptide - Research Areas
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BACKGROUND
This gene encodes the enzyme responsible for formation ofthe blood group I antigen. The i and I antigens are distinguishedby linear and branched poly-N-acetyllactosaminoglycans,respectively. The encoded protein is the I-branching enzyme, abeta-1,6-N-acetylglucosaminyltransferase responsible for theconversion of fetal i antigen to adult I antigen in erythrocytesduring embryonic development. Mutations in this gene have beenassociated with adult i blood group phenotype. Alternativelyspliced transcript variants encoding different isoforms have beendescribed.
REFERENCES
Twu, Y.C., et al. Blood 110(13):4526-4534(2007)Wang, L., et al. Biochem. Biophys. Res. Commun. 331(4):958-963(2005)Pras, E., et al. Invest. Ophthalmol. Vis. Sci. 45(6):1940-1945(2004)Inaba, N., et al. Blood 101(7):2870-2876(2003)Yu, L.C., et al. Blood 101(6):2081-2088(2003)
