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KATL1 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9BW62 |
|---|---|
| Other Accession | NP_115492.1, NP_001014402.1 |
| Clone Names | 91119046 |
| Gene ID | 84056 |
|---|---|
| Other Names | Katanin p60 ATPase-containing subunit A-like 1 {ECO:0000255|HAMAP-Rule:MF_03024}, Katanin p60 subunit A-like 1 {ECO:0000255|HAMAP-Rule:MF_03024}, 3643 {ECO:0000255|HAMAP-Rule:MF_03024}, p60 katanin-like 1 {ECO:0000255|HAMAP-Rule:MF_03024}, KATNAL1 {ECO:0000255|HAMAP-Rule:MF_03024} |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | KATNAL1 {ECO:0000255|HAMAP-Rule:MF_03024} |
|---|---|
| Function | Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays (By similarity). Has microtubule- severing activity in vitro (PubMed:26929214). |
| Cellular Location | Cytoplasm, cytoskeleton {ECO:0000255|HAMAP- Rule:MF_03024, ECO:0000269|PubMed:22654668}. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Note=Colocalizes with microtubules throughout the basal and adluminal compartments of Sertoli cells (By similarity). Localizes within the cytoplasm, partially overlapping with microtubules, in interphase and to the mitotic spindle and spindle poles during mitosis (PubMed:26929214). {ECO:0000250|UniProtKB:Q8K0T4, ECO:0000269|PubMed:26929214} |
| Tissue Location | Expressed in testis, restricted to Sertoli cells (at protein level). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Dunham, A., et al. Nature 428(6982):522-528(2004)Millar, J.K., et al. Biochem. Biophys. Res. Commun. 311(4):1019-1025(2003)Robertson, N.G., et al. Genomics 23(1):42-50(1994)
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