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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   CD22 Antibody (Center) Blocking peptide   

CD22 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P20273
Other Accession NP_001762.2, NP_001172028.1, NP_001172030.1, NP_001172029.1
Clone Names 90713037
Peptide ID 90713037
Additional Information
Gene ID 933
Other Names B-cell receptor CD22, B-lymphocyte cell adhesion molecule, BL-CAM, Sialic acid-binding Ig-like lectin 2, Siglec-2, T-cell surface antigen Leu-14, CD22, CD22, SIGLEC2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD22
Synonyms SIGLEC2
Function Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location B-lymphocytes.
Research Areas
Citations (0)

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Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Uckun, F.M., et al. Proc. Natl. Acad. Sci. U.S.A. 107(39):16852-16857(2010)Ramya, T.N., et al. Mol. Cell Proteomics 9(6):1339-1351(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)El-Sayed, Z.A., et al. Egypt J Immunol 16(1):27-38(2009)

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$ 80.00
Cat# BP10233c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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