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GAS2L1 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q99501 |
|---|---|
| Other Accession | NP_689422.1, NP_689423.1, NP_006469.2 |
| Clone Names | 91102196 |
| Gene ID | 10634 |
|---|---|
| Other Names | GAS2-like protein 1, GAS2-related protein on chromosome 22, Growth arrest-specific protein 2-like 1, GAS2L1, GAR22 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | GAS2L1 |
|---|---|
| Synonyms | GAR22 |
| Function | Involved in the cross-linking of microtubules and microfilaments (PubMed:12584248, PubMed:24706950). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (PubMed:24706950). |
| Cellular Location | Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber. Note=Colocalizes with the tips of microtubule plus ends. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene, a member of the GAS2family, is similar in sequence to the mouse protein Gas2, anactin-associated protein expressed at high levels ingrowth-arrested cells. Expression of the mouse Gas2 gene isnegatively regulated by serum and growth factors. Three transcriptvariants encoding two different isoforms have been found for thisgene.
References
Saito, A., et al. Psychiatry Res (2010) In press :Gamper, I., et al. Exp. Hematol. 37(5):539-548(2009)Olsen, J.V., et al. Cell 127(3):635-648(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)Goriounov, D., et al. J. Cell. Sci. 116 (PT 6), 1045-1058 (2003) :
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