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FHOD3 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q2V2M9 |
|---|---|
| Other Accession | NP_079411.2 |
| Clone Names | 91009104 |
| Gene ID | 80206 |
|---|---|
| Other Names | FH1/FH2 domain-containing protein 3, Formactin-2, Formin homolog overexpressed in spleen 2, hFHOS2, FHOD3, FHOS2, KIAA1695 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | FHOD3 |
|---|---|
| Synonyms | FHOS2, KIAA1695 |
| Function | Actin-organizing protein that may cause stress fiber formation together with cell elongation (By similarity). Isoform 4 may play a role in actin filament polymerization in cardiomyocytes. |
| Cellular Location | Cytoplasm, cytoskeleton. Note=Main part of the protein localizes to actin fibers and the remaining part displays filamentous staining |
| Tissue Location | Expressed in the heart, kidney and brain. May be down-regulated in various types of heart diseases, including idiopathic dilated, ventricular dilated, familial dilated and perinatal dilated cardiomyopathies, as well as ischemic heart disease (at protein level) |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Proteins that contain formin (FMN1; MIM 136535) homology(FH) domains, such as FHOD3, play a role in regulation of the actincytoskeleton (Kanaya et al., 2005 [PubMed 15966898]).[supplied byOMIM].
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Adkins, D.E., et al. Mol. Psychiatry (2010) In press :Taniguchi, K., et al. J. Biol. Chem. 284(43):29873-29881(2009)French, D., et al. Blood 113(19):4512-4520(2009)Kanaya, H., et al. Genes Cells 10(7):665-678(2005)
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