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L2HGDH Antibody (Center) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9H9P8
Other Accession NP_079160.1
Clone Names 91102294
Peptide ID 91102294
Additional Information
Gene ID 79944
Other Names L-2-hydroxyglutarate dehydrogenase, mitochondrial, Duranin, L2HGDH, C14orf160
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name L2HGDH
Synonyms C14orf160
Cellular Location Mitochondrion.
Tissue Location Widely expressed. Highly expressed in brain, testis and muscle. Expressed to a lower extent in lymphocytes, fibroblasts, keratinocytes, placenta, bladder, small intestine, liver and bone marrow.
Research Areas
Citations (0)

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Background

This gene encodes L-2-hydroxyglutarate dehydrogenase, aFAD-dependent enzyme that oxidizes L-2-hydroxyglutarate toalpha-ketoglutarate in a variety of mammalian tissues. Mutations inthis gene cause L-2-hydroxyglutaric aciduria, a rare autosomalrecessive neurometabolic disorder resulting in moderate to severemental retardation.

References

Short, A.D., et al. Vet. Rec. 167(12):455-457(2010)Steenweg, M.E., et al. Hum. Mutat. 31(4):380-390(2010)Kranendijk, M., et al. Hum. Mutat. 31(3):279-283(2010)Vilarinho, L., et al. J. Hum. Genet. 55(1):55-58(2010)Haliloglu, G., et al. Neuropediatrics 39(2):119-122(2008)

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$ 80.00
Cat# BP10255c
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
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