|Other Names||Sn1-specific diacylglycerol lipase alpha, DGL-alpha, 311-, Neural stem cell-derived dendrite regulator, DAGLA, C11orf11, KIAA0659, NSDDR|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||C11orf11, KIAA0659, NSDDR|
|Function||Catalyzes the hydrolysis of diacylglycerol (DAG) to 2- arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. Required for axonal growth during development and for retrograde synaptic signaling at mature synapses.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Highly expressed in brain and pancreas.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a diacylglycerol lipase. The encodedenzyme is involved in the biosynthesis of the endocannabinoid2-arachidonoyl-glycerol.
Knight, M.A., et al. Hum. Mol. Genet. 17(24):3847-3853(2008)Jung, K.M., et al. Mol. Pharmacol. 68(5):1196-1202(2005)Bisogno, T., et al. J. Cell Biol. 163(3):463-468(2003)
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