|Other Names||Sn1-specific diacylglycerol lipase alpha, DGL-alpha, 311-, Neural stem cell-derived dendrite regulator, DAGLA, C11orf11, KIAA0659, NSDDR|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||C11orf11, KIAA0659, NSDDR|
|Function||Catalyzes the hydrolysis of diacylglycerol (DAG) to 2- arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. Required for axonal growth during development and for retrograde synaptic signaling at mature synapses.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Highly expressed in brain and pancreas.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a diacylglycerol lipase. The encodedenzyme is involved in the biosynthesis of the endocannabinoid2-arachidonoyl-glycerol.
Knight, M.A., et al. Hum. Mol. Genet. 17(24):3847-3853(2008)Jung, K.M., et al. Mol. Pharmacol. 68(5):1196-1202(2005)Bisogno, T., et al. J. Cell Biol. 163(3):463-468(2003)
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