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HOXA10 Antibody (Center) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession P31260
Other Accession NP_061824.3, NP_714926.1
Clone Names 91013120
Peptide ID 91013120
Additional Information
Gene ID 3206
Other Names Homeobox protein Hox-A10, Homeobox protein Hox-18, Homeobox protein Hox-1H, PL, HOXA10, HOX1H
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HOXA10
Synonyms HOX1H
Function Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to the DNA sequence 5'-AA[AT]TTTTATTAC-3'.
Cellular Location Nucleus.
Research Areas
Citations (0)

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Background

In vertebrates, the genes encoding the class oftranscription factors called homeobox genes are found in clustersnamed A, B, C, and D on four separate chromosomes. Expression ofthese proteins is spatially and temporally regulated duringembryonic development. This gene is part of the A cluster onchromosome 7 and encodes a DNA-binding transcription factor thatmay regulate gene expression, morphogenesis, and differentiation.More specifically, it may function in fertility, embryo viability,and regulation of hematopoietic lineage commitment. Alternativelyspliced transcript variants encoding different isoforms have beendescribed.

References

Du, H., et al. Biol. Reprod. 83(2):205-211(2010)Cheng, W., et al. J. Cancer Res. Clin. Oncol. 136(8):1221-1227(2010)Liatsikos, S.A., et al. Reprod. Biomed. Online 21(1):126-132(2010)Godbole, G., et al. J. Reprod. Immunol. 85(2):130-139(2010)Ko, S.Y., et al. Mol. Cell. Endocrinol. 317 (1-2), 112-119 (2010) :

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$ 80.00
Cat# BP10276c
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