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HOXA10 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P31260 |
|---|---|
| Other Accession | NP_061824.3, NP_714926.1 |
| Clone Names | 91013120 |
| Gene ID | 3206 |
|---|---|
| Other Names | Homeobox protein Hox-A10, Homeobox protein Hox-18, Homeobox protein Hox-1H, PL, HOXA10, HOX1H |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | HOXA10 |
|---|---|
| Synonyms | HOX1H |
| Function | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to the DNA sequence 5'-AA[AT]TTTTATTAC-3'. |
| Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
In vertebrates, the genes encoding the class oftranscription factors called homeobox genes are found in clustersnamed A, B, C, and D on four separate chromosomes. Expression ofthese proteins is spatially and temporally regulated duringembryonic development. This gene is part of the A cluster onchromosome 7 and encodes a DNA-binding transcription factor thatmay regulate gene expression, morphogenesis, and differentiation.More specifically, it may function in fertility, embryo viability,and regulation of hematopoietic lineage commitment. Alternativelyspliced transcript variants encoding different isoforms have beendescribed.
References
Du, H., et al. Biol. Reprod. 83(2):205-211(2010)Cheng, W., et al. J. Cancer Res. Clin. Oncol. 136(8):1221-1227(2010)Liatsikos, S.A., et al. Reprod. Biomed. Online 21(1):126-132(2010)Godbole, G., et al. J. Reprod. Immunol. 85(2):130-139(2010)Ko, S.Y., et al. Mol. Cell. Endocrinol. 317 (1-2), 112-119 (2010) :
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