|Other Names||Transcription factor Spi-C, SPIC|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression (By similarity).|
|Tissue Location||Preferentially detected in fetal and adult spleen, lymph nodes and at lower levels in bone marrow and fetal liver.|
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Provided below are standard protocols that you may find useful for product applications.
Carlsson, R., et al. Biochem. Biophys. Res. Commun. 344(4):1155-1160(2006)Carlsson, R., et al. Gene 299 (1-2), 271-278 (2002) :
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