|Other Names||Centrosomal protein of 89 kDa, Cep89, Centrosomal protein 123, Cep123, Coiled-coil domain-containing protein 123, CEP89, CCDC123|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Required for ciliogenesis. Also plays a role in mitochondrial metabolism where it may modulate complex IV activity.|
|Cellular Location||Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Mitochondrion intermembrane space. Note=Localizes to the distal appendage region of the centriole, which anchors the mother centriole to the plasma membrane|
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Provided below are standard protocols that you may find useful for product applications.
Kottgen, A., et al. Nat. Genet. 42(5):376-384(2010)Chambers, J.C., et al. Nat. Genet. 42(5):373-375(2010)Hahn, Y., et al. Hum. Genet. 119 (1-2), 169-178 (2006) :
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