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LRRC33 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q86YC3
Other Accession NP_940967.1
Clone Names 100111067
Peptide ID 100111067
Additional Information
Gene ID 375387
Other Names Negative regulator of reactive oxygen species, Leucine-rich repeat-containing protein 33, NRROS, LRRC33
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms LRRC33
Function Negative regulator of reactive oxygen species (ROS) that limits ROS production by phagocytes during inflammatory response, thereby playing a role during host defense. Acts via direct interaction with CYBB/NOX2 monomer that impairs interaction between CYBB/NOX2 and CYBA/p22-phox and formation of a stable NOX2 complex (By similarity). May play a critical role in desensitizing TLR signaling through inhibition of Toll-like receptor-mediated NF-kappa-B activation and cytokine production.
Cellular Location Cell membrane; Single-pass type I membrane protein Endoplasmic reticulum membrane; Single-pass type I membrane protein
Tissue Location Ubiquitous, with high level of expression found in bone marrow, thymus, liver, lung, intestine and spleen
Research Areas
Citations (0)

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Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)

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$ 80.00
Cat# BP10317b
(40 western blots)
Availability: In Stock
Bulk Size
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