|Other Accession||NP_001138578.1, NP_116232.3|
|Other Names||Fibrinogen C domain-containing protein 1, FIBCD1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Acetyl group-binding receptor which shows a high- affinity and calcium-dependent binding to acetylated structures such as chitin, some N-acetylated carbohydrates, and amino acids, but not to their non-acetylated counterparts. Can facilitate the endocytosis of acetylated components.|
|Cellular Location||Membrane; Single-pass type II membrane protein|
|Tissue Location||Expressed in the small and large intestinal epithelial cells with a highly polarized localization to the apical surface corresponding to the brush border and in the ducts of the salivary gland.|
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Provided below are standard protocols that you may find useful for product applications.
FIBCD1 is a conserved type II transmembrane endocyticreceptor that binds chitin and is located primarily in theintestinal brush border (Schlosser et al., 2009 [PubMed19710473]).
Davila, S., et al. Genes Immun. 11(3):232-238(2010)Thomsen, T., et al. J. Biol. Chem. 285(2):1229-1238(2010)Schlosser, A., et al. J. Immunol. 183(6):3800-3809(2009)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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