|Other Names||Dynein regulatory complex protein 1, Coiled-coil domain-containing protein 164, DRC1, C2orf39, CCDC164|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Required for the assembly and regulation of specific classes of inner dynein arm motors. May also function to restrict dynein-driven microtubule sliding, thus aiding in the generation of ciliary bending.|
|Cellular Location||Cytoplasm, cytoskeleton, cilium axoneme|
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Provided below are standard protocols that you may find useful for product applications.
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
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