|Other Names||Radial spoke head protein 9 homolog, RSPH9, C6orf206, MRPS18AL1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Probable component of the axonemal radial spoke head. Radial spokes are regularly spaced along cilia, sperm and flagella axonemes. They consist of a thin stalk, which is attached to a subfiber of the outer doublet microtubule, and a bulbous head, which is attached to the stalk and appears to interact with the projections from the central pair of microtubules.|
|Cellular Location||Cytoplasm, cytoskeleton, cilium axoneme. Note=Radial spoke.|
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This gene encodes a protein thought to be a component ofthe radial spoke head in motile cilia and flagella. Mutations inthis gene are associated with primary ciliary dyskinesia 12.Alternative splicing results in multiple transcript variants.
Reish, O., et al. Ann. Hum. Genet. 74(2):117-125(2010)Castleman, V.H., et al. Am. J. Hum. Genet. 84(2):197-209(2009)Mungall, A.J., et al. Nature 425(6960):805-811(2003)
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