|Other Names||WAP four-disulfide core domain protein 12, Putative protease inhibitor WAP12, Whey acidic protein 2, WFDC12, C20orf122, WAP2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Antibacterial protein. Putative acid-stable proteinase inhibitor.|
|Tissue Location||Highly expressed in prostate, skin, lung and esophagus. Weakly expressed in skeletal muscle, epididymis, kidney, trachea, salivary gland, testis and seminal vesicle|
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This gene encodes a member of the WAP-type four-disulfidecore (WFDC) domain family. The WFDC domain, or WAP signature motif,contains eight cysteines forming four disulfide bonds at the coreof the protein, and functions as a protease inhibitor. Most WFDCgene members are localized to chromosome 20q12-q13 in two clusters:centromeric and telomeric. This gene belongs to the centromericcluster.
Clauss, A., et al. Biochem. Biophys. Res. Commun. 333(2):383-389(2005)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)Clauss, A., et al. Biochem. J. 368 (PT 1), 233-242 (2002) :Lundwall, A., et al. Biochem. Biophys. Res. Commun. 290(1):452-456(2002)Deloukas, P., et al. Nature 414(6866):865-871(2001)
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