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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   WFDC12 Antibody (C-term) Blocking peptide   

WFDC12 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q8WWY7
Other Accession NP_543145.1
Clone Names 91216267
Peptide ID 91216267
Additional Information
Other Names WAP four-disulfide core domain protein 12, Putative protease inhibitor WAP12, Whey acidic protein 2, WFDC12, C20orf122, WAP2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name WFDC12
Synonyms C20orf122, WAP2
Function Antibacterial protein. Putative acid-stable proteinase inhibitor.
Cellular Location Secreted.
Tissue Location Highly expressed in prostate, skin, lung and esophagus. Weakly expressed in skeletal muscle, epididymis, kidney, trachea, salivary gland, testis and seminal vesicle EMBL; AY037803; AAK68848.1; -; mRNA EMBL; AY358678; AAQ89041.1; -; mRNA EMBL; Z93016; -; NOT_ANNOTATED_CDS; Genomic_DNA CCDS; CCDS13343.1; - RefSeq; NP_543145.1; NM_080869.1 UniGene; Hs.352180; - ProteinModelPortal; Q8WWY7; - SMR; Q8WWY7; - BioGrid; 126126; 1 IntAct; Q8WWY7; 6 STRING; 9606.ENSP00000361871; - MEROPS; I17.003; - iPTMnet; Q8WWY7; - PhosphoSitePlus; Q8WWY7; - BioMuta; WFDC12; - DMDM; 24212610; - PaxDb; Q8WWY7; - PeptideAtlas; Q8WWY7; - PRIDE; Q8WWY7; - ProteomicsDB; 74959; - DNASU; 128488; - Ensembl; ENST00000372785; ENSP00000361871; ENSG00000168703 GeneID; 128488; - KEGG; hsa:128488; - UCSC; uc002xnf.2; human CTD; 128488; - EuPathDB; HostDB:ENSG00000168703.5; - GeneCards; WFDC12; - HGNC; HGNC:16115; WFDC12 MIM; 609872; gene neXtProt; NX_Q8WWY7; - OpenTargets; ENSG00000168703; - PharmGKB; PA25663; - eggNOG; ENOG410JHHC; Eukaryota eggNOG; ENOG41119G0; LUCA GeneTree; ENSGT00390000012286; - HOGENOM; HOG000133110; - HOVERGEN; HBG055877; - InParanoid; Q8WWY7; - OMA; DPPQCHT; - OrthoDB; EOG091G1A64; - PhylomeDB; Q8WWY7; - TreeFam; TF338375; - GenomeRNAi; 128488; - PRO; PR:Q8WWY7; - Proteomes; UP000005640; Chromosome 20 Bgee; ENSG00000168703; - CleanEx; HS_WFDC12; - Genevisible; Q8WWY7; HS GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; NAS:UniProtKB GO; GO:0042742; P:defense response to bacterium; ISS:UniProtKB Gene3D;; -; 1 InterPro; IPR036645; Elafin-like_sf InterPro; IPR008197; WAP_dom Pfam; PF00095; WAP; 1 PRINTS; PR00003; 4DISULPHCORE SMART; SM00217; WAP; 1 SUPFAM; SSF57256; SSF57256; 1 PROSITE; PS51390; WAP; 1 1: Evidence at protein level; Antibiotic; Antimicrobial; Complete proteome; Disulfide bond; Protease inhibitor; Reference proteome; Secreted; Serine protease inhibitor; Signal SIGNAL 1 23 CHAIN 24 111 WAP four-disulfide core domain protein 12 /FTId=PRO_0000041390 DOMAIN 27 74 WAP. {ECO:0000255|PROSITE- ProRule:PRU00722} DISULFID 34 62 {ECO:0000255|PROSITE-ProRule:PRU00722} DISULFID 41 66 {ECO:0000255|PROSITE-ProRule:PRU00722} DISULFID 49 61 {ECO:0000255|PROSITE-ProRule:PRU00722} DISULFID 55 70 {ECO:0000255|PROSITE-ProRule:PRU00722} SEQUENCE 111 AA; 12050 MW; 2DFB39043F1A0997 CRC64; MGSSSFLVLM VSLVLVTLVA VEGVKEGIEK AGVCPADNVR CFKSDPPQCH TDQDCLGERK CCYLHCGFKC VIPVKELEEG GNKDEDVSRP YPEPGWEAKC PGSSSTRCPQ K
Research Areas
Citations (0)

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This gene encodes a member of the WAP-type four-disulfidecore (WFDC) domain family. The WFDC domain, or WAP signature motif,contains eight cysteines forming four disulfide bonds at the coreof the protein, and functions as a protease inhibitor. Most WFDCgene members are localized to chromosome 20q12-q13 in two clusters:centromeric and telomeric. This gene belongs to the centromericcluster.


Clauss, A., et al. Biochem. Biophys. Res. Commun. 333(2):383-389(2005)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)Clauss, A., et al. Biochem. J. 368 (PT 1), 233-242 (2002) :Lundwall, A., et al. Biochem. Biophys. Res. Commun. 290(1):452-456(2002)Deloukas, P., et al. Nature 414(6866):865-871(2001)

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Cat# BP10369b
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