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XKR8 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9H6D3
Other Accession NP_060523.2
Clone Names 91230018
Additional Information
Gene ID 55113
Other Names XK-related protein 8, hXkr8, XK-related protein 8, processed form, XKR8, XRG8
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name XKR8 {ECO:0000303|PubMed:23845944, ECO:0000312|HGNC:HGNC:25508}
Function [XK-related protein 8, processed form]: Phospholipid scramblase that promotes phosphatidylserine exposure on apoptotic cell surface (PubMed:23845944, PubMed:25231987). Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment (PubMed:23845944). Required for the clearance of apoptotic cells, such as engulfment of apoptotic germ cells by Sertoli cells, clearance of senescent neutrophils or regulation of bipolar cell numbers in the retina (By similarity). Has no effect on calcium-induced exposure of phosphatidylserine (PubMed:23845944). Promotes myoblast differentiation and survival (PubMed:28881496).
Cellular Location Cell membrane; Multi-pass membrane protein. Cytoplasm, perinuclear region
Research Areas
Citations (0)
citation

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References

Gregory, S.G., et al. Nature 441(7091):315-321(2006)

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$ 277.78
Cat# BP10378b
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