SLC35B4 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q969S0 |
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Other Accession | NP_116215.1 |
Clone Names | 91102191 |
Gene ID | 84912 |
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Other Names | UDP-xylose and UDP-N-acetylglucosamine transporter, Solute carrier family 35 member B4, YEA4 homolog, SLC35B4, YEA4 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SLC35B4 |
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Synonyms | YEA4 |
Function | Antiporter that transports nucleotide sugars across the endoplasmic reticulum (ER) membrane in exchange for another nucleotide sugar. May couple UDP-alpha-D-glucuronate (UDP-GlcA) or UDP-alpha-D- xylose (UDP-Xyl) efflux to UDP-alpha-D-glucuronate (UDP-GlcA) influx into the ER lumen, which in turn stimulates glucuronidation and excretion of endobiotics and xenobiotics. |
Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
Glycosyltransferases, such as SLC35B4, transportnucleotide sugars from the cytoplasm where they are synthesized, tothe Golgi apparatus where they are utilized in the synthesis ofglycoproteins, glycolipids, and proteoglycans (Ashikov et al., 2005[PubMed 15911612]).
References
Kobayashi, T., et al. Biochem. J. 400(2):281-289(2006)Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)Ashikov, A., et al. J. Biol. Chem. 280(29):27230-27235(2005)
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