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SLC35B4 Antibody (Center) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q969S0
Other Accession NP_116215.1
Clone Names 91102191
Additional Information
Gene ID 84912
Other Names UDP-xylose and UDP-N-acetylglucosamine transporter, Solute carrier family 35 member B4, YEA4 homolog, SLC35B4, YEA4
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC35B4
Synonyms YEA4
Function Antiporter that transports nucleotide sugars across the endoplasmic reticulum (ER) membrane in exchange for another nucleotide sugar. May couple UDP-alpha-D-glucuronate (UDP-GlcA) or UDP-alpha-D- xylose (UDP-Xyl) efflux to UDP-alpha-D-glucuronate (UDP-GlcA) influx into the ER lumen, which in turn stimulates glucuronidation and excretion of endobiotics and xenobiotics.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Research Areas
Citations (0)
citation

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Background

Glycosyltransferases, such as SLC35B4, transportnucleotide sugars from the cytoplasm where they are synthesized, tothe Golgi apparatus where they are utilized in the synthesis ofglycoproteins, glycolipids, and proteoglycans (Ashikov et al., 2005[PubMed 15911612]).

References

Kobayashi, T., et al. Biochem. J. 400(2):281-289(2006)Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)Ashikov, A., et al. J. Biol. Chem. 280(29):27230-27235(2005)

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$ 277.78
Cat# BP10395c
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