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COBL Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O75128
Other Accession NP_056013.2
Clone Names 91109307
Peptide ID 91109307
Additional Information
Gene ID 23242
Other Names Protein cordon-bleu, COBL, KIAA0633
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KIAA0633
Function Plays an important role in the reorganization of the actin cytoskeleton. Regulates neuron morphogenesis and increases branching of axons and dendrites. Regulates dendrite branching in Purkinje cells (By similarity). Binds to and sequesters actin monomers (G actin). Nucleates actin polymerization by assembling three actin monomers in cross-filament orientation and thereby promotes growth of actin filaments at the barbed end. Can also mediate actin depolymerization at barbed ends and severing of actin filaments. Promotes formation of cell ruffles.
Cellular Location Cell membrane; Peripheral membrane protein; Cytoplasmic side Cytoplasm, cytoskeleton. Cell projection, ruffle. Cytoplasm. Note=Recruited to the cell membrane via interaction with PACSIN1. Colocalizes with the actin cytoskeleton. Detected throughout the neuron cell body, as well as in axons and dendrites (By similarity).
Research Areas
Citations (0)

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Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Trynka, G., et al. Gut 58(8):1078-1083(2009)Barrett, J.C., et al. Nat. Genet. (2009) In press :de Krom, M., et al. Biol. Psychiatry 65(7):625-630(2009)Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004)

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$ 80.00
Cat# BP10402a
(40 western blots)
Availability: In Stock
Bulk Size
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