|Other Accession||NP_055509.2, NP_001138792.1|
|Other Names||ADAMTS-like protein 2, ADAMTSL-2, ADAMTSL2, KIAA0605|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the ADAMTS (a disintegrinand metalloproteinase with thrombospondin motifs) and ADAMTS-likeprotein family. Members of the family share several distinctprotein modules, including a propeptide region, a metalloproteinasedomain, a disintegrin-like domain, and a thrombospondin type 1 (TS)motif. Individual members of this family differ in the number ofC-terminal TS motifs, and some have unique C-terminal domains. Theprotein encoded by this gene lacks the protease domain, and istherefore of a member of the the ADAMTS-like protein subfamily. Itis a secreted glycoprotein that binds the cell surface andextracellular matrix; it also interacts with latent transforminggrowth factor beta binding protein 1. Mutations in this gene havebeen associated with geleophysic dysplasia.
Le Goff, C., et al. Nat. Genet. 40(9):1119-1123(2008)Koo, B.H., et al. Matrix Biol. 26(6):431-441(2007)Hall, N.G., et al. Matrix Biol. 22(6):501-510(2003)
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