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ATL2 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q86TH1 |
|---|---|
| Other Accession | NP_055509.2, NP_001138792.1 |
| Clone Names | 91201006 |
| Gene ID | 9719 |
|---|---|
| Other Names | ADAMTS-like protein 2, ADAMTSL-2, ADAMTSL2, KIAA0605 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ADAMTSL2 |
|---|---|
| Synonyms | KIAA0605 |
| Cellular Location | Secreted. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the ADAMTS (a disintegrinand metalloproteinase with thrombospondin motifs) and ADAMTS-likeprotein family. Members of the family share several distinctprotein modules, including a propeptide region, a metalloproteinasedomain, a disintegrin-like domain, and a thrombospondin type 1 (TS)motif. Individual members of this family differ in the number ofC-terminal TS motifs, and some have unique C-terminal domains. Theprotein encoded by this gene lacks the protease domain, and istherefore of a member of the the ADAMTS-like protein subfamily. Itis a secreted glycoprotein that binds the cell surface andextracellular matrix; it also interacts with latent transforminggrowth factor beta binding protein 1. Mutations in this gene havebeen associated with geleophysic dysplasia.
References
Le Goff, C., et al. Nat. Genet. 40(9):1119-1123(2008)Koo, B.H., et al. Matrix Biol. 26(6):431-441(2007)Hall, N.G., et al. Matrix Biol. 22(6):501-510(2003)
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