|Other Names||Rab GTPase-activating protein 1, GAP and centrosome-associated protein, Rab6 GTPase-activating protein GAPCenA, RABGAP1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May act as a GTPase-activating protein of RAB6A. May play a role in microtubule nucleation by centrosome. May participate in a RAB6A-mediated pathway involved in the metaphase- anaphase transition.|
|Cellular Location||Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Predominantly cytosolic but also associated with the centrosome|
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Provided below are standard protocols that you may find useful for product applications.
RABGAP1 may act as a GTPase-activating protein of RAB6A and play a role in microtubule nucleation by centrosome. It may participate in a RAB6A-mediated pathway involved in the metaphase-anaphase transition.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Ishibashi, K., et al. Genes Cells 14(1):41-52(2009)Echard, A., et al. Mol. Biol. Cell 11(11):3819-3833(2000)Opdam, F.J., et al. J. Cell. Sci. 113 (PT 15), 2725-2735 (2000) :Cuif, M.H., et al. EMBO J. 18(7):1772-1782(1999)
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