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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   CCR8 Antibody (C-term) Blocking Peptide   

CCR8 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P51685
Other Accession NP_005192.1
Clone Names 91019020
Peptide ID 91019020
Additional Information
Gene ID 1237
Other Names C-C chemokine receptor type 8, C-C CKR-8, CC-CKR-8, CCR-8, CC chemokine receptor CHEMR1, CMKBRL2, Chemokine receptor-like 1, CKR-L1, GPR-CY6, GPRCY6, TER1, CDw198, CCR8, CKRL1, CMKBR8, CMKBRL2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CCR8
Function Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection.
Cellular Location Cell membrane; Multi-pass membrane protein.
Research Areas
Citations (0)

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CCR8 encodes a member of the beta chemokine receptorfamily, which is predicted to be a seven transmembrane proteinsimilar to G protein-coupled receptors. Chemokines and theirreceptors are important for the migration of various cell typesinto the inflammatory sites. This receptor protein preferentiallyexpresses in the thymus. I-309, thymus activation-regulatedcytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1beta) have been identified as ligands of this receptor. Studies ofthis receptor and its ligands suggested its role in regulation ofmonocyte chemotaxis and thymic cell apoptosis. More specifically,this receptor may contribute to the proper positioning of activatedT cells within the antigenic challenge sites and specialized areasof lymphoid tissues. CCR8 is located at the chemokine receptorgene cluster region.


Mutalithas, K., et al. Clin. Exp. Allergy 40(8):1175-1185(2010)Han, S., et al. Hum. Immunol. 71(7):727-730(2010)Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 18(5):1651-1658(2009)

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$ 80.00
Cat# BP10485b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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