|Other Accession||NP_060882.2, NP_068708.1|
|Other Names||Suppressor of tumorigenicity 7 protein, Protein FAM4A1, Protein HELG, ST7, FAM4A1, HELG, RAY1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||FAM4A1, HELG, RAY1|
|Function||May act as a tumor suppressor.|
|Cellular Location||Membrane; Multi-pass membrane protein|
|Tissue Location||Ubiquitously expressed, with highest levels in heart, liver and pancreas.|
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Provided below are standard protocols that you may find useful for product applications.
The gene for this product maps to a region on chromosome 7identified as an autism-susceptibility locus. Mutation screening ofthe entire coding region in autistic individuals failed to identifyphenotype-specific variants, suggesting that coding mutations forthis gene are unlikely to be involved in the etiology of autism.The function of this gene product has not been determined.Transcript variants encoding different isoforms of this proteinhave been described.
Bailey, S.D., et al. Diabetes Care (2010) In press :Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Guilmatre, A., et al. Arch. Gen. Psychiatry 66(9):947-956(2009)de Krom, M., et al. Biol. Psychiatry 65(7):625-630(2009)
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