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AP3S1 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q92572
Other Accession NP_001275.1
Clone Names 91102193
Additional Information
Gene ID 1176
Other Names AP-3 complex subunit sigma-1, AP-3 complex subunit sigma-3A, Adaptor-related protein complex 3 subunit sigma-1, Clathrin-associated/assembly/adaptor protein, small 3, Sigma-3A-adaptin, Sigma3A-adaptin, Sigma-adaptin 3a, AP3S1, CLAPS3
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name AP3S1
Synonyms CLAPS3
Function Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
Cellular Location Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex
Tissue Location Present in all adult tissues examined.
Research Areas
Citations (0)
citation

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Background

Part of the AP-3 complex, an adapter-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Zhou, J.B., et al. Med. Sci. Monit. 16 (6), BR179-BR183 (2010) :Lefrancois, S., et al. Dev. Cell 7(4):619-625(2004)Salazar, G., et al. Mol. Biol. Cell 15(2):575-587(2004)Nie, Z., et al. Dev. Cell 5(3):513-521(2003)

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$ 277.78
Cat# BP10499a
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