|Other Accession||NP_543020.2, NP_570612.1|
|Other Names||Cystatin-11, CST11, CST8L|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Has antibacterial activity against the Gram-negative bacteria E.coli. May play a role in sperm maturation and fertilization.|
|Cellular Location||Nucleus. Cytoplasm. Note=Nuclear and cytoplasmic in the epididymis. Localized to the postacrosomal and tail regions of sperm. Probably localized to the outer surface of sperm|
|Tissue Location||Detected in the epithelium and lumen of the epididymis, and in sperm (at protein level)|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The cystatin superfamily encompasses proteins that containmultiple cystatin-like sequences. Some of the members are activecysteine protease inhibitors, while others have lost or perhapsnever acquired this inhibitory activity. There are three inhibitoryfamilies in the superfamily, including the type 1 cystatins(stefins), type 2 cystatins and the kininogens. The type 2 cystatinproteins are a class of cysteine proteinase inhibitors found in avariety of human fluids and secretions. The cystatin locus onchromosome 20 contains the majority of the type 2 cystatin genesand pseudogenes. CST11 is located in the cystatin locus andencodes an epididymal-specific protein whose specific function hasnot been determined. Alternative splicing yields two variantsencoding distinct isoforms.
Hamil, K.G., et al. Endocrinology 143(7):2787-2796(2002)Deloukas, P., et al. Nature 414(6866):865-871(2001)Brown, W.M., et al. Protein Sci. 6(1):5-12(1997)Dickinson, D.P., et al. Genomics 24(1):172-175(1994)Thiesse, M., et al. DNA Cell Biol. 13(2):97-116(1994)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.