|Other Accession||NP_003035.3, NP_001116320.1, NP_001116319.1|
|Other Names||Sodium- and chloride-dependent betaine transporter, BGT-1, Na(+)/Cl(-) betaine/GABA transporter, Solute carrier family 6 member 12, SLC6A12|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Liver, heart, skeletal muscle, placenta, and a widespread distribution in the brain|
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Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation.
Pasaje, C.F., et al. Ann. Hum. Genet. 74(4):326-334(2010)Kottgen, A., et al. Nat. Genet. 42(5):376-384(2010)Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :Chapuis, J., et al. Mol. Psychiatry 14(11):1004-1016(2009)Gratacos, M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009) :
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