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MCAF2 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q5U623
Other Accession NP_079273.2
Clone Names 91201012
Peptide ID 91201012
Additional Information
Gene ID 80063
Other Names Activating transcription factor 7-interacting protein 2, ATF7-interacting protein 2, MBD1-containing chromatin-associated factor 2, ATF7IP2, MCAF2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ATF7IP2
Synonyms MCAF2
Function Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity (Probable).
Cellular Location Nucleus.
Research Areas
Citations (0)

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Background

Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone 'Lys-9' trimethylation activity (Probable).

References

Adkins, D.E., et al. Mol. Psychiatry (2010) In press :Ichimura, T., et al. J. Biol. Chem. 280(14):13928-13935(2005)

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$ 80.00
Cat# BP10509c
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