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DEN5A Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q6IQ26 |
|---|---|
| Other Accession | NP_056028.2 |
| Clone Names | 91201047 |
| Gene ID | 23258 |
|---|---|
| Other Names | DENN domain-containing protein 5A, Rab6-interacting protein 1, Rab6IP1, DENND5A, KIAA1091, RAB6IP1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | DENND5A |
|---|---|
| Synonyms | KIAA1091, RAB6IP1 |
| Function | Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Involved in the negative regulation of neurite outgrowth (By similarity). |
| Cellular Location | Golgi apparatus membrane {ECO:0000250|UniProtKB:Q6PAL8} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
May be involved in Rab6-mediated GTPase signaling.
References
Recacha, R., et al. Structure 17(1):21-30(2009)Olsen, J.V., et al. Cell 127(3):635-648(2006)Janoueix-Lerosey, I., et al. J. Biol. Chem. 270(24):14801-14808(1995)
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