|Other Names||DENN domain-containing protein 5A, Rab6-interacting protein 1, Rab6IP1, DENND5A, KIAA1091, RAB6IP1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.|
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Provided below are standard protocols that you may find useful for product applications.
May be involved in Rab6-mediated GTPase signaling.
Recacha, R., et al. Structure 17(1):21-30(2009)Olsen, J.V., et al. Cell 127(3):635-648(2006)Janoueix-Lerosey, I., et al. J. Biol. Chem. 270(24):14801-14808(1995)
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