|Other Accession||NP_113661.2, NP_001137251.1, NP_054774.2|
|Other Names||Intraflagellar transport protein 81 homolog, Carnitine deficiency-associated protein expressed in ventricle 1, CDV-1, IFT81, CDV1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Component of the intraflagellar transport (IFT) complex B: together with IFT74, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds tubulin via its CH (calponin-homology)-like region. Required for ciliogenesis.|
|Cellular Location||Cell projection, cilium|
|Tissue Location||Highly expressed in testis, moderately in ovary, heart, liver, skeletal muscle, kidney and pancreas, low in prostate, brain, placenta and lung and not detected in spleen, thymus, small intestine and colon. Isoform CDV-1R is abundantly expressed in testis.|
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Provided below are standard protocols that you may find useful for product applications.
Isoform CDV-1 may be involved in cardiac hypertrophy caused by carnitine deficiency (By similarity).Isoform CDV-1R appears to play a role in development of the testis and spermatogenesis (By similarity).
Melzer, D., et al. PLoS Genet. 4 (5), E1000072 (2008) :Lamesch, P., et al. Genomics 89(3):307-315(2007)Peng, J., et al. Mol. Biol. Rep. 29(4):353-362(2002)Higashi, M., et al. Mamm. Genome 11(12):1053-1057(2000)
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