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N4BP1 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession O75113
Other Accession NP_694574.3
Clone Names 91201242
Peptide ID 91201242
Additional Information
Gene ID 9683
Other Names NEDD4-binding protein 1, N4BP1, N4BP1, KIAA0615
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name N4BP1
Synonyms KIAA0615
Function Inhibitor of the E3 ubiquitin-protein ligase ITCH. Acts by interacting with the second WW domain of ITCH, leading to compete with ITCH's substrates and impairing ubiquitination of substrates (By similarity).
Cellular Location Nucleus, nucleolus. Nucleus, PML body. Note=Primarily localizes to the nucleolus Also localizes to the PML nuclear bodies, when desumoylated (By similarity).
Tissue Location Detected in heart, lung, brain, liver, skeletal muscle, pancreas, kidney, spleen, testis and ovary
Research Areas
Citations (0)

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Background

Inhibitor of the E3 ubiquitin-protein ligase ITCH. Acts by interacting with the second WW domain of ITCH, leading to compete with ITCH's substrates and impairing ubiquitination of substrates (By similarity).

References

Enjuanes, A., et al. Cancer Res. 68(24):10178-10186(2008)Matsuoka, S., et al. Science 316(5828):1160-1166(2007)Anantharaman, V., et al. RNA Biol 3(1):18-27(2006)Murillas, R., et al. J. Biol. Chem. 277(4):2897-2907(2002)

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$ 80.00
Cat# BP10518a
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