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N4BP1 Antibody (N-term) Blocking PeptideSynthetic peptide

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United States
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Ordering Information
Catalog # Size Availability Price  
BP10518a 0.1 mg 400 ul In Stock $ 45.00 Add to cart
  • Specification
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  • Backgrounds

N4BP1 Antibody (N-term) Blocking Peptide - Product info

Primary AccessionO75113
Other AccessionNP_694574.3
Clone Names91201242
Calculated MW100379 Da

N4BP1 Antibody (N-term) Blocking Peptide - Additional info

Gene ID 9683
Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Precautions
This product is for research use only. Not for use in diagnostic or therapeutic procedures.

N4BP1 Antibody (N-term) Blocking Peptide - Protein Information

Name N4BP1
Synonyms KIAA0615
Function
Inhibitor of the E3 ubiquitin-protein ligase ITCH. Acts by interacting with the second WW domain of ITCH, leading to compete with ITCH's substrates and impairing ubiquitination of substrates (By similarity)
Cellular Location
Nucleus, nucleolus (By similarity). Nucleus, PML body (By similarity). Note=Primarily localizes to the nucleolus. Also localizes to the PML nuclear bodies, when desumoylated (By similarity)
Tissue Location
Detected in heart, lung, brain, liver, skeletal muscle, pancreas, kidney, spleen, testis and ovary

N4BP1 Antibody (N-term) Blocking Peptide - Related products

AP10518a: N4BP1 Antibody (N-term)

BP10518a: N4BP1 Antibody (N-term) Blocking Peptide

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

Inhibitor of the E3 ubiquitin-protein ligase ITCH. Acts by interacting with the second WW domain of ITCH, leading to compete with ITCH's substrates and impairing ubiquitination of substrates (By similarity).

REFERENCES

Enjuanes, A., et al. Cancer Res. 68(24):10178-10186(2008)Matsuoka, S., et al. Science 316(5828):1160-1166(2007)Anantharaman, V., et al. RNA Biol 3(1):18-27(2006)Murillas, R., et al. J. Biol. Chem. 277(4):2897-2907(2002)