FSTL1 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q12841 |
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Other Accession | NP_009016.1 |
Clone Names | 91216015 |
Gene ID | 11167 |
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Other Names | Follistatin-related protein 1, Follistatin-like protein 1, FSTL1, FRP |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | FSTL1 |
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Synonyms | FRP |
Function | Secreted glycoprotein that is involved in various physiological processes, such as angiogenesis, regulation of the immune response, cell proliferation and differentiation (PubMed:29212066, PubMed:22265692). Plays a role in the development of the central nervous system, skeletal system, lungs, and ureter (By similarity). Promotes endothelial cell survival, migration and differentiation into network structures in an AKT-dependent manner. Also promotes survival of cardiac myocytes (By similarity). Initiates various signaling cascades by activating different receptors on the cell surface such as DIP2A, TLR4 or BMP receptors (PubMed:20054002, PubMed:22265692). |
Cellular Location | Secreted. |
Tissue Location | Overexpressed in synovial tissues from rheumatoid arthritis (PubMed:15638044). |
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Provided below are standard protocols that you may find useful for product applications.
References
Kai, N., et al. Brain Res. 1073-1074, 60-70 (2006) :Venter, J.C., et al. Science 291(5507):1304-1351(2001)
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