|Other Names||Lymphocyte antigen 6 complex locus protein G6c, LY6G6C, C6orf24, G6C, NG24|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||C6orf24, G6C, NG24|
|Cellular Location||Cell membrane; Lipid-anchor, GPI-anchor|
|Tissue Location||Highly expressed at the leading edges of cells, on filopodia.|
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Provided below are standard protocols that you may find useful for product applications.
LY6G6C belongs to a cluster of leukocyte antigen-6 (LY6)genes located in the major histocompatibility complex (MHC) classIII region on chromosome 6. Members of the LY6 superfamilytypically contain 70 to 80 amino acids, including 8 to 10cysteines. Most LY6 proteins are attached to the cell surface by aglycosylphosphatidylinositol (GPI) anchor that is directly involvedin signal transduction (Mallya et al., 2002 [PubMed12079290]).
Bailey, S.D., et al. Diabetes Care (2010) In press :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009) :Xie, T., et al. Genome Res. 13(12):2621-2636(2003)Mallya, M., et al. Genomics 80(1):113-123(2002)
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