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SCARF2 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q96GP6
Other Accession NP_878315.1, NP_699165.2
Clone Names 91218299
Additional Information
Gene ID 91179
Other Names Scavenger receptor class F member 2, SRECRP-1, Scavenger receptor expressed by endothelial cells 2 protein, SREC-II, SCARF2, SREC2, SREPCR
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SCARF2
Synonyms SREC2, SREPCR
Function Probable adhesion protein, which mediates homophilic and heterophilic interactions. In contrast to SCARF1, it poorly mediates the binding and degradation of acetylated low density lipoprotein (Ac- LDL) (By similarity).
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Predominantly expressed in endothelial cells. Expressed in heart, placenta, lung, kidney, spleen, small intestine and ovary.
Research Areas
Citations (0)
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Background

The protein encoded by this gene is similar toSCARF1/SREC-I, a scavenger receptor protein that mediates thebinding and degradation of acetylated low density lipoprotein(Ac-LDL). This protein has only little activity of internalizingmodified low density lipoproteins (LDL), but it can interact withSCARF1 through its extracellular domain. The association of thisprotein with SCARF1 is suppressed by the presence of scavengerligands. Alternatively spliced transcript variants encodingdistinct isoforms have been reported.

References

Anastasio, N., et al. Am. J. Hum. Genet. 87(4):553-559(2010)Wu, C., et al. Proteomics 7(11):1775-1785(2007)Ishii, J., et al. J. Biol. Chem. 277(42):39696-39702(2002)

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$ 277.78
Cat# BP10542b
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