|Other Accession||NP_878315.1, NP_699165.2|
|Other Names||Scavenger receptor class F member 2, SRECRP-1, Scavenger receptor expressed by endothelial cells 2 protein, SREC-II, SCARF2, SREC2, SREPCR|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Probable adhesion protein, which mediates homophilic and heterophilic interactions. In contrast to SCARF1, it poorly mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL) (By similarity).|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Predominantly expressed in endothelial cells. Expressed in heart, placenta, lung, kidney, spleen, small intestine and ovary.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is similar toSCARF1/SREC-I, a scavenger receptor protein that mediates thebinding and degradation of acetylated low density lipoprotein(Ac-LDL). This protein has only little activity of internalizingmodified low density lipoproteins (LDL), but it can interact withSCARF1 through its extracellular domain. The association of thisprotein with SCARF1 is suppressed by the presence of scavengerligands. Alternatively spliced transcript variants encodingdistinct isoforms have been reported.
Anastasio, N., et al. Am. J. Hum. Genet. 87(4):553-559(2010)Wu, C., et al. Proteomics 7(11):1775-1785(2007)Ishii, J., et al. J. Biol. Chem. 277(42):39696-39702(2002)
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