CCDC40 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q4G0X9 |
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Other Accession | NP_060420.2 |
Clone Names | 91230012 |
Gene ID | 55036 |
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Other Names | Coiled-coil domain-containing protein 40, CCDC40, KIAA1640 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CCDC40 (HGNC:26090) |
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Function | Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella (PubMed:21131974). Probably acts together with CCDC39 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (By similarity). Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39 (PubMed:21131974). |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q8BI79}. Cell projection, cilium. Note=Localizes to cytoplasm and motile cilium. {ECO:0000250|UniProtKB:Q8BI79} |
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Provided below are standard protocols that you may find useful for product applications.
References
Kimura, K., et al. Genome Res. 16(1):55-65(2006)Ota, T., et al. Nat. Genet. 36(1):40-45(2004)Strausberg, R.L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002)Nagase, T., et al. DNA Res. 7(4):273-281(2000)
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