ANKRD16 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q6P6B7 |
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Other Accession | NP_001009943.1, NP_061919.1, NP_001009941.1 |
Clone Names | 91230171 |
Gene ID | 54522 |
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Other Names | Ankyrin repeat domain-containing protein 16, ANKRD16 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ANKRD16 (HGNC:23471) |
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Function | Required to prevent the misactivation of serine (Ser) with tRNA(Ala) by promoting the hydrolysis of Ser-mischarged tRNA(Ala), thereby playing a role in translational fidelity. Binds directly to the catalytic domain of AARS/AlaRS and captures Ser that is misactivated by AARS/AlaRS, preventing the charging of Ser adenylates to tRNA(Ala) and precluding Ser misincorporation in nascent peptides. |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:A2AS55}. Nucleus {ECO:0000250|UniProtKB:A2AS55} |
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Provided below are standard protocols that you may find useful for product applications.
References
Turnbull, C., et al. Nat. Genet. 42(6):504-507(2010)Lamesch, P., et al. Genomics 89(3):307-315(2007)Deloukas, P., et al. Nature 429(6990):375-381(2004)
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