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CLEC10A Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8IUN9
Other Accession NP_878910.1, NP_006335.2
Clone Names 91230197
Peptide ID 91230197
Additional Information
Gene ID 10462
Other Names C-type lectin domain family 10 member A, C-type lectin superfamily member 14, Macrophage lectin 2, CD301, CLEC10A, CLECSF13, CLECSF14, HML
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CLEC10A
Synonyms CLECSF13, CLECSF14, HML
Function Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells.
Cellular Location Membrane; Single-pass type II membrane protein
Research Areas
Citations (0)

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Background

CLEC10A encodes a member of the C-type lectin/C-typelectin-like domain (CTL/CTLD) superfamily. Members of this familyshare a common protein fold and have diverse functions, such ascell adhesion, cell-cell signalling, glycoprotein turnover, androles in inflammation and immune response. The encoded type 2transmembrane protein may function as a cell surface antigen. Twotranscript variants encoding distinct isoforms have been identifiedfor this gene.

References

Davila, S., et al. Genes Immun. 11(3):232-238(2010)Iijima, M., et al. Neurology 73(17):1348-1352(2009)van Vliet, S.J., et al. PLoS Pathog. 5 (10), E1000625 (2009) :Suzuki, N., et al. J. Immunol. 156(1):128-135(1996)

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$ 80.00
Cat# BP10558a
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