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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   KIAA1530 Antibody (N-term) Blocking Peptide   

KIAA1530 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q2YD98
Other Accession NP_065945.2
Clone Names 100111073
Peptide ID 100111073
Additional Information
Gene ID 57654
Other Names UV-stimulated scaffold protein A, UVSSA, KIAA1530
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KIAA1530
Function Factor involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage. TC-NER allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Acts by promoting stabilization of ERCC6 by recruiting deubiquitinating enzyme USP7 to TC-NER complexes, preventing UV-induced degradation of ERCC6 by the proteasome. Interacts with the elongating form of RNA polymerase II (RNA pol IIo) and facilitates its ubiquitination at UV damage sites, leading to promote RNA pol IIo backtracking to allow access to the nucleotide excision repair machinery. Not involved in processing oxidative damage.
Cellular Location Chromosome. Note=Accumulates at UV DNA damage sites
Research Areas
Citations (0)

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Lamesch, P., et al. Genomics 89(3):307-315(2007)

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$ 80.00
Cat# BP10583a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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