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LACE1 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8WV93
Other Accession NP_660358.2
Clone Names 100111270
Peptide ID 100111270
Additional Information
Gene ID 246269
Other Names Lactation elevated protein 1, Protein AFG1 homolog, LACE1, AFG1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name AFG1L (HGNC:16411)
Function Putative mitochondrial ATPase. Plays a role in mitochondrial morphology and mitochondrial protein metabolism. Promotes degradation of excess nuclear-encoded complex IV subunits (COX4I1, COX5A and COX6A1) and normal activity of complexes III and IV of the respiratory chain (PubMed:26759378, PubMed:27323408). Mediates mitochondrial translocation of TP53 and its transcription-independent apoptosis in response to genotoxic stress (PubMed:27323408).
Cellular Location Mitochondrion membrane
Research Areas
Citations (0)

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Background

LACE1 encodes a protein with possible ATPase function.The protein contains a P-loop motif and a five-domain structurethat is conserved in fly, yeast, and bacteria. Two conservedestrogen receptor binding sites are located within 2.5 kb of thisgene.

References

Bailey, S.D., et al. Diabetes Care (2010) In press :Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Mattar, R., et al. Clin. Biochem. 41 (7-8), 628-630 (2008) :Abrahams, B.S., et al. Genomics 80(1):45-53(2002)

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$ 80.00
Cat# BP10615a
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