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NGRN Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NPE2 |
|---|---|
| Other Accession | NP_001028260.2 |
| Clone Names | 100120099 |
| Gene ID | 51335 |
|---|---|
| Other Names | Neugrin, Mesenchymal stem cell protein DSC92, Neurite outgrowth-associated protein, Spinal cord-derived protein FI58G, NGRN, FI58G |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | NGRN {ECO:0000303|PubMed:27667664, ECO:0000312|HGNC:HGNC:18077} |
|---|---|
| Function | Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system. |
| Cellular Location | Nucleus. Secreted. Mitochondrion membrane |
| Tissue Location | Expressed at high levels in heart, brain and skeletal muscle. In brain, mainly expressed in neurons rather than glial cells. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Olfactory receptors interact with odorant molecules in thenose, to initiate a neuronal response that triggers the perceptionof a smell. The olfactory receptor proteins are members of a largefamily of G-protein-coupled receptors (GPCR) arising from singlecoding-exon genes. Olfactory receptors share a 7-transmembranedomain structure with many neurotransmitter and hormone receptorsand are responsible for the recognition and G protein-mediatedtransduction of odorant signals. The olfactory receptor gene familyis the largest in the genome. The nomenclature assigned to theolfactory receptor genes and proteins for this organism isindependent of other organisms.
References
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)Malnic, B., et al. Proc. Natl. Acad. Sci. U.S.A. 101(8):2584-2589(2004)Bulger, M., et al. Proc. Natl. Acad. Sci. U.S.A. 97(26):14560-14565(2000)Bulger, M., et al. Proc. Natl. Acad. Sci. U.S.A. 96(9):5129-5134(1999)
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