|Other Names||Protein ARV1, hARV1, ARV1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role as a mediator in the endoplasmic reticulum (ER) cholesterol and bile acid homeostasis (PubMed:11063737, PubMed:12145310, PubMed:20663892). Participates in sterol transport out of the ER and distribution into plasma membranes (PubMed:20663892).|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein|
|Tissue Location||Ubiquitous. Highly expressed in liver and adipose.|
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May act as a mediator of sterol homeostasis (Potential).
Tong, F., et al. J. Biol. Chem. 285(44):33632-33641(2010)Lamesch, P., et al. Genomics 89(3):307-315(2007)Swain, E., et al. J. Biol. Chem. 277(39):36152-36160(2002)Tinkelenberg, A.H., et al. J. Biol. Chem. 275(52):40667-40670(2000)
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