|Other Names||Glypican-5, Secreted glypican-5, GPC5|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Cell surface proteoglycan that bears heparan sulfate.|
|Cellular Location||Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side|
|Tissue Location||In adult, primarily expressed in the brain. Also detected in fetal brain, lung and liver|
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Provided below are standard protocols that you may find useful for product applications.
Cell surface heparan sulfate proteoglycans are composed ofa membrane-associated protein core substituted with a variablenumber of heparan sulfate chains. Members of the glypican-relatedintegral membrane proteoglycan family (GRIPS) contain a coreprotein anchored to the cytoplasmic membrane via a glycosylphosphatidylinositol linkage. These proteins may play a role inthe control of cell division and growth regulation. [provided byRefSeq].
Lorentzen, A.R., et al. J. Neuroimmunol. 226 (1-2), 194-197 (2010) :Landi, M.T., et al. Lancet Oncol. 11(8):714-716(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Li, Y., et al. Lancet Oncol. 11(4):321-330(2010)Arking, D.E., et al. PLoS ONE 5 (3), E9879 (2010) :
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