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PON1 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P27169
Clone Names 90713163
Peptide ID 90713163
Additional Information
Gene ID 5444
Other Names Serum paraoxonase/arylesterase 1, PON 1, Aromatic esterase 1, A-esterase 1, K-45, Serum aryldialkylphosphatase 1, PON1, PON
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PON1
Synonyms PON
Function Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.
Cellular Location Secreted, extracellular space.
Tissue Location Plasma, associated with HDL (at protein level). Expressed in liver, but not in heart, brain, placenta, lung, skeletal muscle, kidney or pancreas
Research Areas
Citations (0)

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The enzyme encoded by this gene is an arylesterase thatmainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is anorganophosphorus anticholinesterase compound that is produced invivo by oxidation of the insecticide parathion. Polymorphisms inthis gene are a risk factor in coronary artery disease. The gene isfound in a cluster of three related paraoxonase genes at 7q21.3.


Ergun, M.A., et al. Biochem. Genet. (2010) In press :Cagirci, G., et al. J. Heart Valve Dis. 19(4):453-458(2010)Mendonca, M.I., et al. Rev Port Cardiol 29(4):571-580(2010)Hashemi, M., et al. Genet. Mol. Res. 9(3):1735-1741(2010)Martinez, C., et al. BMC Neurol 10, 71 (2010) :

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$ 80.00
Cat# BP10684c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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