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UBE2M Antibody (C-term) Blocking PeptideSynthetic peptide
| Country | United States
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| Catalog # | Size | Availability | Price | |
| BP1068b | 0.1 mg 400 ul | In Stock | $ 45.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
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UBE2M Antibody (C-term) Blocking Peptide - Product info | |
| Primary Accession | P61081 |
| Other Accession | NP_003960 |
| Clone Names | 2112204 |
| Calculated MW | 20900 Da |
UBE2M Antibody (C-term) Blocking Peptide - Additional info | |
| Gene ID 9040 | |
| Target/Specificity The synthetic peptide sequence used to generate the antibody AP1068b was selected from the C-term region of human UBE2M. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. | |
| Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
UBE2M Antibody (C-term) Blocking Peptide - Protein Information | |
| Name UBE2M | |
| Synonyms UBC12 | |
| Function Accepts the ubiquitin-like protein NEDD8 from the UBA3- NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. Involved in cell proliferation | |
UBE2M Antibody (C-term) Blocking Peptide - Related products
AP1068a: UBE2M Antibody (N-term)
AP1068b: UBE2M Antibody (C-term)
AP2169a: UBE2M Antibody (N-term K11)
AP2169b: UBE2M Antibody (Center)
RI15581: UBE2M predesign siRNA
LY11934a: UBE2M Over-expression Lysate
BP1068a: UBE2M Antibody (N-term) Blocking Peptide
BP1068b: UBE2M Antibody (C-term) Blocking Peptide
BP2169a: UBE2M Antibody (N-term K11) Blocking Peptide
UBE2M Antibody (C-term) Blocking Peptide - Research Areas
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BACKGROUND
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin.
REFERENCES
Gong, L., et al., J. Biol. Chem. 274(17):12036-12042 (1999).Osaka, F., et al., Genes Dev. 12(15):2263-2268 (1998).
